Oct.31.2021 会议日程

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  江会锋

  天津工业生物技术研究所副所长

  TBD

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  Shyam  PRABHAKAR

  新加坡基因组研究所高级研究员；系统生物学和数据分析实验室副主任

  Single-cell Analysis of Asian Diversity and Colorectal Cancer: Algorithms and Applications

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  郭国骥

  浙江大学医学院教授，博士生导师

  从细胞景观推断遗传模型

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  Xiaojie QIU

  麻省理工学院霍华德休斯医学研究所

  绘制单个细胞的转录组向量场

  Single-cell (sc)-RNA-seq, together with RNA-velocity and metabolic labeling, reveals cellular states and transitions at unprecedented resolution. Fully exploiting these data, however, requires kinetic models capable of unveiling governing regulatory functions. Here, we introduce an analytical framework dynamo, that infers absolute RNA velocity by overcoming intrinsic limitations of conventional RNA velocity analyses based solely on splicing data, reconstructs continuous vector-field functions that predict future cell fates, employs differential geometry to extract underlying regulatory networks, and ultimately predicts optimal reprogramming paths and perturbation outcomes. We highlight dynamo’s power to enable accurate velocity estimations on a metabolically-labeled human hematopoiesis scRNA-seq dataset. Furthermore, differential geometry analyses reveal the mechanism driving early appearance of megakaryocytes and elucidate asymmetrical regulation within the PU.1–GATA1 circuit. Leveraging the Least-Action-Path method, dynamo accurately predicts specific drivers of numerous hematopoietic transitions. Finally, in silico perturbations predict cell-fate diversions induced by gene perturbations. Dynamo thus represents an important step in advancing quantitative and predictive theories of cell-state transitions.
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  徐健

  中国科学院青岛生物能源与过程所研究员

  Ramanome、FlowRACS 和 RACS-Seq：将单细胞代谢表型和基因组连接起来用于合成生物学和精准医学

  A single-cell is the unit of function and evolution for life forms on Earth, therefore establishing the link between metabolic phenome and genome (and transcriptome, etc) is of fundamental importance. We have proposed “Ramanome” as a type of single-cell metabolic phenome that is non-invasive, label-free, information-rich, ultrafast, high-throughput, low-cost and universally applicable. Then the IRCA (Intra-Ramanome Correlation Analysis) algorithm was introduced, which unveils a network of metabolite conversion based on a single instance of a single sample. Furthermore, we invented a series of Raman-activated Cell Sorters, such as RACS-Seq and FlowRACS (www.singlecellbiotech.com), to sort and sequence individual human, algal, fungal and bacterial cells with targeted metabolic phenome via their single-cell Raman spectra. The advantages of RACS-Seq and FlowRACS as compared to FACS (Fluorescence-activated Cell Sorting) have been demonstrated in screening novel enzymes and cell factories, and for distinguishing and sorting individual drug-resistance cells (cancers and pathogens). As metabolic phenome directly captures the “function” of a cell, ramanome and FlowRACS/RACS-Seq have become powerful new tools for synthetic biology and precision medicine.
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  韩磊

  华大细胞数字化中心

  成年非人灵长类猕猴的细胞转录组图谱

  Studying tissue composition and function in non-human primates (NHP) is crucial to understand the nature of our own species. Here, we present a large-scale cell transcriptomic atlas encompassing over one million cells from 45 tissues from the adult NHP Macaca fascicularis. This dataset provides a vast and carefully annotated resource to study a species phylogenetically close to humans. To demonstrate its utility, we have reconstructed the cell-cell interaction networks driving Wnt signalling across the body, mapped the distribution of receptors and co-receptors for viruses causing human infectious diseases, and intersected our data with human genetic disease orthologous coordinates to establish potential clinical associations. Our Macaca fascicularis cell atlas constitutes an essential reference for future studies in human and NHP.
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  马丽佳

  西湖大学

  TBD

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  李亦学

  中科院计算生物学重点实验室副主任，计算基因组学和大数据课题组组长

  新数据密集型科学研究范式及其技术支撑

  The nature of the computer operating system is to solve the application complexity of the hardware used by the user. The content of the computer operating system includes system libraries, development platforms, applications, data management, data storage, etc. When computing application development becomes more and more complex, a complete set of systems is needed to shield the complex underlying architecture. The purpose of the emergence of operating systems, such as scene-based operating systems, and new technology operating systems, etc., is to reduce the complexity of application development. The biomedical big data "operating system (Bio-OS)" is to solve four major problems: 1. The system development and construction standards are not uniform, 2. The application and resources are scattered, 3. The convenient development environment is lacking, 4. The technology platform of the general architecture is lacking. "Bio-OS" is an open source, open, new R&D environment and biomedical information "operating system" that supports the "new data-intensive scientific research paradigm". Its significance and value in the industry and research field is no less than the significance and industry status of the "Android system" developed by Google in the field of mobile communications. As a software engineering to fill gaps in the field, the "operating system" of the biomedical big data industry and research field is undoubtedly cutting-edge and disruptive.
• 

  田瑞军

  南方科技大学化学系终身教授，博士生导师，加拿大渥太华大学医学院及深圳市人民医院兼职教授，担任蛋白质、化学相关的多个组织理事职务

  蛋白质组学驱动的胰腺癌研究

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  任艳

  华大基因、领域技术支持专家

  结直肠腺瘤和癌的上皮和间质蛋白质组比较

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  曹亚南

  上海交通大学研究员，博士生导师，主要研究方向为内分泌代谢病的临床和基础研究

  中国人群队列的基因分型和多基因风险评分研究

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  徐书华

  中国科学院特聘研究员

  亚洲热带土著民族的遗传联系和趋同进化

  Tropical indigenous peoples in Asia (TIA) attract much attention for their unique appearance, while their genetic history and adaptive evolution remain mysteries. We conducted a comprehensive study to characterize the genetic distinction and connection of broad geographical TIAs. Despite TIA groups show diverse genetic makeup and large inter-area genetic differentiation, we identified a basal Asian ancestry (bASN) specifically shared by these populations. Interestingly, bASN was relatively enriched in ancient Asian human genomes dated as early as ~50,000 years before the present, and diminished in more recent history. Notably, bASN was unlikely derived from archaic hominins but rather modeled as a survived lineage of the initial peopling of Asia. Shared adaptations inherited from the ancient Asian ancestry were detected among DSI groups (e.g., LIMS1 for hair morphology, and COL24A1 for bone formation), and they are enriched in neurological functions at an identical locus (e.g., NKAIN3) or different loci in an identical gene (e.g., TENM4). Phenotypic convergence of the dark skin in TIAs could have resulted from parallel (e.g., DDB1) or genetic convergence driven by admixture (e.g., MTHFD1 and RAD18), new mutations (e.g., STK11), and notably purifying selection (e.g., MC1R). Our results provided new insights into the initial peopling of Asia and an advanced understanding of the phenotypic convergence of TIA peoples.
• 

  王传超

  教授、博士生导师 厦门大学人类学研究所所长

  Asia古基因组学解析东亚史前人群迁徙和语言传播历史

  东亚人群的起源和演化受到了学术界和大众的广泛关注。在经历了人体测量学、考古和古人类学的探索和争论之后，古基因组学方法的介入使得这一问题越来越明朗。我们对中国陕西新石器时代五庄果墚遗址、中国台湾新石器到铁器时代汉本和公馆遗址、蒙古国50余个考古遗址、俄罗斯远东地区Boisman、Yankovsky和黑水靺鞨等遗址、日本绳文人遗址等距今8000到1000年前166个古人基因组进行了捕获测序，对中国和尼泊尔46个现代族群的383个样本的芯片分型数据以及108个考古碳十四测年数据。利用古DNA数据检验了东亚地区农业和语言共扩散理论，发现（1）汉藏同源：5000年前黄河流域的农业人群在中国北方传播农耕、汉藏语言和相关技术，在遗传上成为了藏族和汉族的共同祖先人群之一；（2）南岛与壮侗同源：3000-2000年前台湾的古人与大陆壮侗语人群有紧密的遗传关系，南岛语人群形成过程中还受到来自北方农业人群的基因混合影响，南岛和壮侗的祖先人群向南扩张，传播南岛语和壮侗语，并对南亚语人群有遗传贡献；(3)自蒙古高原、贝加尔湖到黑龙江流域的广大地区的8000多年前的采集狩猎人群与其后的蒙古和通古斯语人群有着较强的遗传连续性，在遗传上并未明显受到来自农业人群的影响，反驳了语言学家Martine Robbeets提出的西辽河农业人群的扩张促成了原始泛欧亚语（Transeurasian）传播的假说。人群大规模的迁徙和混合使得东亚地区人群之间的遗传差异越来越小，现代的东亚族群之间的差异比8000年前减少了至少4倍。研究人员还观察到日本绳文时期、中国台湾、东南亚等新石器到铁器时代的古人群有遗传上的联系，表明他们的一部分祖先人群可能来自共同的早期沿海迁徙路线，这与早期分子人类学上所观察到的旧石器时代Y染色体单倍群D的分布相吻合。研究者们发现8000多年前蒙古国的采集狩猎人群与黑龙江流域的采集狩猎人群在遗传上非常相似，而在5000年前青铜时代早中期颜那亚草原游牧人群从欧洲向东扩张进入蒙古，而后被4000-3500年前到来的青铜时代中晚期草原游牧人群所取代，在2000年前左右又有与汉族有关的遗传成分进入到蒙古。该研究还从古DNA角度对汉族人群的源流做出了分析，认为南北方汉族的祖先人群主要是由新石器时代南北方农业人群混合形成的，由北向南呈现梯度混合模式。
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  刘军

  中国疾病预防控制中心研究员

  The omics study on the immune responses to SARS-CoV-2

  The coronavirus disease 2019 (COVID-19) pandemic poses a current world-wide public health threat. We preformed series of omics-based investigations to study the immune hallmarks of COVID-19 compared to other infectious diseases. Firstly, we integrated single-cell RNA sequencing (scRNA-seq) to describe the transcriptional landscape of longitudinally collected peripheral blood mononuclear cells (PBMCs) in both COVID-19- and influenza A virus (IAV)-infected patients. We observed distinct signaling pathways activated in COVID-19 (STAT1 and IRF3) versus IAV (STAT3 and NFkB) patients and substantial differences in the expression of key factors. Meanwhile, the scRNA-seq, together with the cell-free circulating RNAs (cfRNAs) sequencing in plasma indicated that increase of interleukin (IL) 6R and IL6ST expression in COVID-19 patients. The cfRNA landscape of COVID-19 patient plasma also showed that miR-451a, a known negative regulator of IL-6R translation, was downregulated, correlating with three upregulated long noncoding RNAs (lncRNAs) carrying miR-451a binding sites. Recently, we present an integrated analysis of urine and serum proteomics and clinical measurements in convalescent cases of COVID-19, and found that prolonged dysregulation of the immune response and cholesterol metabolism might be the pivotal causative agent of other potential sequelae. Thus, we unveiled the distinct landscape of immune responses in COVID-19 patients and convalescents through multi-omics.
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  王超龙

  华中科技大学同济医学院公共卫生学院教授，博士生导师

  东南亚独特的土生华人华人人口中的遗传混合物

  The Peranakan Chinese are culturally unique descendants of immigrants from China who settled in the Malay Archipelago ~300-500 years ago. Today, among large communities in Southeast Asia, the Peranakans have preserved Chinese traditions with strong influence from the local indigenous Malays. Yet, whether or to what extent genetic admixture co-occurred with the cultural mixture has been a topic of ongoing debate. We performed whole-genome sequencing (WGS) on 177 Singapore (SG) Peranakans and analyzed the data jointly with WGS data of Asian and European populations. We estimated that Peranakan Chinese inherited ~5.62% (95% confidence interval [CI]: 4.75-6.46%) Malay ancestry, much higher than that in SG Chinese (1.08%, 0.69-1.53%), southern Chinese (0.86%, 0.57-1.31%), and northern Chinese (0.25%, 0.18-0.33%). A sex-biased admixture history, in which the Malay ancestry was contributed primarily by females, was supported by X chromosomal variants, and mitochondrial (MT) and Y haplogroups. Finally, we identified an ancient admixture event shared by Peranakan Chinese and SG Chinese ~1,612 (95% CI: 1,345-1,923) years ago, coinciding with the settlement history of Han Chinese in southern China, apart from the recent admixture event with Malays unique to Peranakan Chinese ~190 (159-213) years ago. These findings greatly advance our understanding of the dispersal history of Chinese and their interaction with indigenous populations in Southeast Asia.
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  沈侠

  中山大学

  ACE2冠状病毒受体的遗传景观

  SARS-CoV-2 and SARS-CoV share the same cell membrane entry receptor, angiotensin-converting enzyme 2 (ACE2), which is thus key to the infection and treatment of the coronavirus. The genetic basis of ACE2 protein levels is not well understood. Here we conduct a genome-wide association meta-analysis of plasma ACE2 levels in over 28,000 individuals of the SCALLOP Consortium. We identified ten loci capturing 30% of the protein’s heritability. We detected that plasma ACE2 was genetically correlated with severe COVID-19 and a wide range of human complex diseases and medications. An X-chromosome cis-pQTL-based Mendelian randomization analysis suggested a causal effect of elevated ACE2 levels on COVID-19 severity, hospitalization, and infection. Tissue- and cell-type-specific transcriptomic and epigenomic analysis revealed that the ACE2 regulatory variants were enriched for DNA methylation sites in blood immune cells. Our results demonstrate the genetic architecture of the ACE2 protein, providing a useful resource for further biological and clinical studies on this coronavirus receptor
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  Shilpa GARG

  哥本哈根大学副教授

  用于复杂疾病综合测序分析的高效、高分辨率生物信息学方法

  
  

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  郭亚龙

  中国科学院植物研究所、研究员

  基因组中的转座元件——不再是垃圾 DNA

  Despite rapid progress in the understanding of diverse genetic variation, what roles transposable elements (TEs) insertions play in the process of adaptive evolution, are largely unknown. For a long time, TEs has been regarded as junk DNA. Based on the genomics and genetics analyses, using Arabidopsis thaliana and its relative Capsella rubella, we demonstrate that transposable elements (TEs) are an important source of genetic variation that could account for high phenotypic diversity, and revealed that TEs could plays important roles in the process of adaptive evolution. Especially, our results imply that the abundant TE insertions could potentially help with adaptation to changing environments in a species with limited standing genetic variation. Overall, our results highlight TEs could play a crucial role in the adaptation.
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  伊廷双

  中国科学院昆明植物研究所研究员

  豆类的系统基因组学

  Fabaceae are the third largest angiosperm family, with 765 genera over 19,500 species. They are important both economically and ecologically, and global Fabaceae crops are intensively studied in part for their nitrogen-fixing ability. However, phylogenetic resolution of the backbone and divergence times remained elusive, precluding a reconstruction of the evolutionary history of symbiotic nitrogen fixation in Fabaceae. Here, we report a highly resolved phylogeny using >1500 nuclear genes from newly sequenced transcriptomes and genomes of 391 species, along with other datasets, for a total of 463 legumes spanning all 6 subfamilies and 333 of 765 genera. We also resolve many of the Leguminosae’s thorniest nodes through comprehensive analyses of plastome-scale data using multiple modified coding and noncoding data sets of 187 species representing almost all major clades of the family. The six subfamilies are maximally supported as monophyletic, and both nuclear and plastid data support Duparquetioideae and Dialioideae are successive sisters to the clade of Papilionoideae and Caesalpinioideae (DDPC), however the nuclear data support the clade comprising subfamilies Detarioideae and Cercidoideae is sister to DDPC, but the plastid data support Detarioideae and Cercidoideae as successive sisters to DDPC. Molecular clock estimation revealed an early radiation of subfamilies near the K/Pg boundary, marked by mass extinction, and subsequent divergence of most tribe-level clades within ca. 15 million years. Phylogenomic analyses of thousands of gene families support 28 proposed putative whole-genome duplication/whole-genome triplication events across Fabaceae, including those at the ancestors of Fabaceae and five of the subfamilies. The evolution of rhizobial nitrogen-fixing nodulation in Fabaceae was probed by ancestral character reconstruction and phylogenetic analyses of related gene families and the results support the hypotheses of one or two switch(es) to rhizobial nodulation followed by multiple losses. Collectively, these results provide a foundation for further morphological and functional evolutionary analyses across Fabaceae.
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  杨辉

  卡尔斯鲁厄理工学院-技术评估和系统分析研究所客座研究员和博士后研究员

  用于基因治疗的 CRISPR/Cas13 介导的 RNA 编辑

  CRISPR/Cas13 is a type of RNA-guided ribonuclease system, which is widely used in the fields of RNA knockdown, RNA base editing, RNA site-directed modification, live cell imaging, and nucleic acid detection. Compared with the traditional RNA interference technology, the Cas13 system showed higher knockdown efficiency and specificity. Moreover, in contrast with Cas9-mediated DNA editing technology, RNA editing by Cas13 will not cause permanent changes to the genome, and can even be achieved in drugs inducible manner to make it reversible. Thus, it has unique advantages for disease treatment in the future.  However, Cas13-based RNA editors are too large to be packaged into a single adeno-associated virus (AAV) vector, which limit their in vivo application. In this talk, we identified two compact families (775 to 803 amino acids (aa)) of CRISPR–Cas ribonucleases from hypersaline samples, named Cas13X and Cas13Y, by analyzing metagenomic terabase datasets. We engineered Cas13X.1 (775 aa) for RNA interference experiments in mammalian cell lines and a minimal RNA base editor (composed of engineered deaminase (385 aa) and truncated Cas13X.1 (445 aa)) for RNA base conversions. Finally, we applied our developed Cas13 system to treat Angelman syndrome and Duchenne muscular dystrophy.
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  罗周卿

  厦门大学生命科学学院教授

  通过从头设计和合成重构真核染色体臂

  Genome evolves by changing its sequence, content and arrangement over time, but the extent to which these aspects can be changed and whether they can be rationally designed is unknown. To probe these questions, we firstly design three structural modules essential for linear chromosome and demonstrate the efficient and faithful linear chromosome assembly by co-transforming them together with sequences encoding desired functions. Expression and function of endogenous genes relocated to this neo-chromosome are indistinguishable to their counterparts in the native locus. Exogenous pathway can also be encoded on this neo-chromosome to produce desired chemicals. Then, several neo-chromosomes were designed, synthesized and tested for their abilities to substitute the left arm of yeast Chr.XII (Chr.XIIL) for survival. Our results showed a neo-chromosome with only 12 genes was enough for the substitution, but addition of other 13 genes improved the strain’s growth. Rationally designed sequences with limited similarity were demonstrated to be able to encode and regulate these genes, and a neo-chromosome composed by them successfully substituted Chr.XIIL for survival. This work highlights the previously unimaginable plasticity of yeast genome, illustrating the feasibility of extensive genome refactor.
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  江湘儿

  深圳华大生命科学研究院/生物技术副研究员

  高通量DNA合成仪的研制与应用

  Comparing with genome sequencing, which facilitates the digitization of life, synthetic biology has enabled human beings to explore the nature of life and promote the cross-disciplinary applications in medicine, chemical industry, agriculture and IT technologies. DNA synthesis serves as the fundamental technology of synthetic biology. The typical process used in synthetically creating DNA is the phosphoramidite method developed in the 1980s. The first-generation of DNA synthesizer (column-based) is widely used till now. It yields well with high fidelity oligos. Since 2004, the second-generation DNA synthesizer (chip-based) has been studied to fulfill demand for rapid development of synthetic biology. The new techniques can synthesize up to one million femtomole scale oligos per run, promoting rapid extension of downstream application such as gene synthesis, oligo pool synthesis and DNA fragment synthesis. Further insights into DNA synthesis technology and its applications will be presented.
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  Ole DOERING

  柏林全球健康研究所教授

  主席介绍——搭建桥梁：让人想起去年关于科学面临新冠病毒和伦理的责任的讨论

  Ethics can support science and technology in their goal to make humanity more sustainably healthy, wealthy and reasonable. What it means to generate responsible innovation depends on the integrity of of practice, in local and global context. Genomics is making bold promises to benefit humanity - which requires humble work to be empowered and aligned according to purpose. Ethics reminds science of the humanity of health and the dignity of wisdom. How can we care better? 
  This session will arrange for an exercise in mutual learning. Experiences from different disciplines, countries and cultural background will be shared. How can the dormant wealth residing within our young generations globally be nourished in order to inspire readiness for an uncertain future? 
  The economic and institutional models that have formed science and technology according to a universal technical standard have promoted a mental monoculture that in effect weakens innovation, creativity and sincerity. Silos and echo chambers need openness for connectivity, so that growth can serve life. After all, it is the fertile input that determines the potential quality of the outcome, together with our supporting infrastructures, not the weighing of quantitative measurements. 
  Based on an advanced holistic understanding of humanity, we can encourage solidarity and humility. 
  We trust in scientists to go beyond the material sciences, in health work to go beyond medicine and in those in power to share, for the benefit of the future. First, let’s listen with care.
  
  
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  Marc Van MONTAGU

  VIB-国际植物生物技术推广（IPBO）名誉教授

  Matter & Mind - I didn’t think about that

  In the Anthropocene, human societies became the agents of the evolution of nature. Through science, we have developed a plethora of tools that have enabled us to survive and thrive. The collateral damage, however, is that we have grown too much. We have bypassed the cycle of natural evolution of our planet. Intensive agriculture plays a central role in this disaster.
  Human ingenuity is the cause, human ingenuity will have to find the remedies. For this we must aim for a pace of scientific discovery that exceeds that of disasters such as the loss of biodiversity, the degradation of ecosystems, epidemics and climate change. But the known generates more of the unknown, and solving a problem always generates new problems that we must solve. We cannot find solutions without understanding how life works. For example, the genetic engineering strategy has allowed us to add new genes to plants. But the concept of one gene one phenotype does not hold up. A trait is the result of a network of biological processes for which we hardly know the genes responsible. If we do not consider the multifactorial arc of systems biology, we will only be making a rough interpretation of what genes do.
  Science has already provided many tools to help humanity reduce global environmental risks and promote global sustainability. But science alone will not solve the problems and shape the future. Innovations for sustainability will be of no use if society does not accept the technology. It is not because we have interesting and useful products that society will accept them quickly. We need to better assess how people will appreciate the result. Much of the problem with the acceptance of GM crops that we have witnessed is the result of actions of ideologies that have taken advantage of our fears and intuitive (emotional) preferences to guide us toward rejection. When ideologies interfere in communication between different actors in society, it will destroy societal values. The use of fake news is immoral and must be openly opposed. The three pillars that support human civilization - society, science and economics - must be properly symmetrical and founded on solid ethical and moral foundations.
  
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  Tilahun YILMA

  地区病毒学名誉教授

  Lords of Poverty: the power, prestige, and corruption of the international aid business

  
  
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  Francis P. CRAWLEY

  欧洲良好临床实践联盟(GCPA)的执行董事，发展伦理审查能力战略倡议(SIDCER)的创始人和主任

  COVID-19 大流行期间的全球合作：生物伦理学如何失败的科学和社会

  The COVID-19 pandemic that followed on the global spread of the SARS-CoV-2 virus was led by great hope and many promises for international cooperation in public health and science. Early on the threat of the rapid spread of a virus with high mortality and morbidity rates was met by politicians, public health experts, scientists, and the international medical community in promises to share resources, data, medicines, and vaccines in an unprecedented movement towards global solidarity, transparency, and openness. All too soon national, organizational, and individual interests began to take center stage. Roadblocks appeared, excuses, and outright refusals to share science and the fruits of science. In this struggle, disappointment, and turmoil, many in society (particularly the weak and the vulnerable) were sidelined, either directly from COVID-19 or from the failures of politicians, scientists, and public health experts to move beyond their specific interests and act in the interest of science, public health, and society. This talk examines the role of bioethics in this failure to achieve global cooperation, perhaps when it was most needed, perhaps when it was most possible.
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  何迪信

  Promoting Citizen Science in Secondary Schools

  中华基金中学校长

  Citizen Science can be described as the practice of public participation and collaboration in scientific research to increase scientific knowledge. Citizen Science plays a crucial role in science education in secondary schools. Secondary school students can be good citizen scientists since they have acquired fundamental concepts from school-based curriculum while they have been equipped with basic project skills. Schools can also make good use of Citizen Science to offer a harmonious venue for establishing learning communities amongst schoolmates, teachers and parents to sparkle citizen science projects with their own learning pace and levels for whole-person development. Students can then scaffold their learning scope widened through collaboration with professional scientists for the sake of the society, levering themselves to be citizen scientists.
  In the talk, the practice of fostering Citizen Science in The Chinese Foundation Secondary School (CFSS) of Hong Kong SAR would be shared. CFSS has incorporated citizen project learning into curriculum to achieve the 17 Sustainable Development Goals(SDGs) advocated by the United Nations. The school has also organized thematic exhibitions and citizen science workshops, in collaboration with Hong Kong Science Museum and Hong Kong Ocean Park to demonstrate highlights of students’ invention and investigation projects on Sustainable Development, outreaching thousands of citizens in the territory.
  

  
  
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  Sonu BHASKAR

  Liverpool Hospital, NSW Brain Clot Bank, Global Health Neurology Lab and Ingham Institute for Applied Medical Research

  Ethics and policy considerations for genomics technologies

  
  
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  Susan WALLACE

  英国莱斯特大学健康科学系人口与公共卫生科学荣誉讲师

  Responsible science and embedding ethics